报告题目：
mTOR regulation of memory CTLs
报告人：肖正国博士, 副教授
Department of Animal and Avian Sciences
University of Maryland
时间：2016年12月27日上午10：00
地点：逸夫楼3036
Lab Information
Our long-term goal is to understand the molecular and cellular mechanisms for the generation of functional cytotoxic T lymphocytes (CTLs) to improve vaccination and cancer therapy. In particular, we are interested in the role of inflammatory cytokines in CTL activation, and their interactions with important pathways during memory CTL development, especially with those related to cell growth and development, such as mTOR and wnt signals. In addition, we are interested in how CTL responses are affected by special physiological conditions such as smoking, diabetes and alcohol abuse. We adopt a wide variety of approaches ranging from basic molecular and cell biology methods to high throughput assays such as proteomics and RNA-seq to understand how CTL functions are influenced both on translational and transcriptional levels.
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